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EVALUATION OF THE ANTIOXIDANT ACTIVITY OF FICUS RACEMOSA PLANT EXTRACTS FROM NORTH-WESTERN DISTRICT OF BANGLADESH

By: Johora Sultana, A.S. Kabir, Md. Abdul Hakim, M. Abdullah, N Islam, Md. Abu Reza

Key Words: Ficus racemosa, plant extract, phenolic conttent, antioxidant.

JLES-Vol-8-No-P-93-99, December 2013

Abstract

Antioxidant is a new hype in naturopathy and at present it has huge demand in cosmetic, nutritional supplementation and pharmacological industry. It reduces cell damages caused by free-radical which are responsible for various ailment like ageing, cancer, coronary heart disease, diabetes mellitus, neurodegenerative disorders, atherosclerosis, cataracts and inflammation. At present any comprehensive data on the antioxidant content and extent of their activity of the indigenous medicinal plants of Bangladesh is not available. Therefore, here antioxidant activity of a popular medicinal plant – Ficus racemosa was determined. Methanolic extract was prepared from the leaf and stem bark of F. racemosa. Their total phenolics and free radical scavenging capacity was determined using folin-ciocalteu reagent (FCR) assay and DPPD-radical scavenging assay respectively. Stem bark and leaves of F. racemosa contains 242.97 and 235.45 mg of GAE / gm of dried extract of phenolics respectively. Current studies also show that F. racemosa barks contain a high antioxidant activity. IC50 value of bark extract was found to be 19µg/ml which is even better that of the standard BHT. Therefore, present studies suggest that F. racemosa bark has a huge potential in terms of commercial use as source of antioxidant.

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  1. Aruoma OI Free radicals, oxidative trace and antioxidants in human health and diseases. J. Am. Oil Chemist’s Soc. 75: 199–212.
  2. Buyukokuroglu ME, Gulcin I, Oktay M and Kufrevioglu OI. In vitro antioxidant properties of dantrolene sodium. Pharmacol. Res. 44: 491- 95.
  3. Cai Y, Sun M and Corke H 2003. Antioxidant activity of betal vines from plants of the Amaranthaceae. Agri. Food Chem. 51: 2288–2294.
  4. Chang C, Yang M, Wen H and Chern J 2002. Estimation of total flavonoid content in Propolis by two complementary colorimetric methods. Food Drug Anal. 10: 178–82.
  5. Choi HY, Jhun EJ, Lim BO, Chng IM, Kyung SH and Park DK Application of flow injection- chemilumineacence to the study of radical scavenging activity in plants. Phytother. Res. 14: 250-253.
  6. Chu YH, Chang CL and Hsu HF 2000. Flavonoid content of several vegetables and their antioxidant activity. Sci. Food and Agri. 80: 561–566.
  7. Cotelle N, Bernier JL, Catteau JP, Pommery J, Wallet JC and Gaydou EM 1996. Antioxidant properties of hydroxyl flavones. Free Radiat. Biol. Med. 20: 35–43.
  8. Desmarchelier C, Repetto M, Coussio J, Liesuy S and Ciccia G Antioxidant and prooxidant activities in aqueous extracts of Argentine plants. Int. J. Pharmacog. 35: 116-120.
  9. Farjana N, Saud ZA, Rahman MH and Haque ME In vitro Antimicrobial Activity of the Compound Isolated from Chloroform Extract of Moringa oleifera Lam. Pakistan J. Biol. Sci. 6(22): 1888-1890.
  10. Gutteridgde JMC 1995. Free radicals in disease processes: A complication of cause and consequence. Free Radic. Res. Comm. 19: 141- 158.
  11. Hamid K, Sultana S, Urmi KF, Ullah MO, Zulfiker AHM and Hossain MA 2011. In vitro free radical scavenging and brine shrimp lithality bioassay of aqueous extract of ficus racemosa Jordan J. Biol. Sci. 4(1): 51-54
  12. Jahan IA, Nahar N, Mosihuzzaman M, Begum MR, Ali L, Khan AK, Makhmur T and Choudhary MI 2009. Hypoglycaemic and antioxidant activities of Ficus racemosa fruits. Nat. Prod. Res. 23(4): 399-408.

Johora Sultana, A.S. Kabir, Md. Abdul Hakim, M. Abdullah, N Islam, Md. Abu Reza

EVALUATION OF THE ANTIOXIDANT ACTIVITY OF FICUS RACEMOSA PLANT EXTRACTS FROM NORTH-WESTERN DISTRICT OF BANGLADESH

JLES-Vol-8-No-P-93-99, December 2013

https://jlescience.com/les-publish/evaluation-of-the-antioxidant-activity-of-ficus-racemosa-plant-extracts-from-north-western-district-of-bangladesh/

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