PREVALENCE AND PATTERN OF INHERITANCE OF ABNORMALITIES RESULTED FROM CONSANGUINEOUS MARRIAGES IN BAGMARA (RAJSHAHI), BANGLADESH
By: Md. Anisur Rahman
Key Words: Consanguineous marriage, first cousin, abnormalities, inheritance pattern
JLES-Vol-9-No-P-21-27-, December 2014
AbstractThe present study assessed the current prevalence of abnormal characters and their pattern of inheritance resulting from first cousin marriages in Bagmara, Rajshahi, Bangladesh. Four types of consanguineous marriages (first cousin) such as marriage between son and daughter of sister and sister, brother and sister, sister and brother and brother and brother were studied in 31 families. Son and daughter or daughter and son marriages were studied for the expression of abnormalities among the children they produced from 20 families of distant relations. Results revealed that first cousin marriages showed expressivity of certain abnormalities i.e., baldness (1.25%), cleft lip (2.50%), deaf and dumb (3.75%), mental retardation (1.25%), polydactyly (3.75%), and squint eyes (2.50%) among the children of consanguineous couples whereas paralysis (2.08%) was found in only one individual in all the children of distant couples. The prevalence of abnormalities in marriage between son and daughter of sister and sister was 22.22%, brother and sister 15.00%, sister and brother 12.00% and brother and brother 11.76%. Children from consanguineous marriages had a higher percentage (15.00%) of abnormalities than that of the distant relations’ marriages (2.08%). In both cases, however, the abnormalities showed autosomal recessive pattern of inheritance.
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Md. Anisur Rahman
PREVALENCE AND PATTERN OF INHERITANCE OF ABNORMALITIES RESULTED FROM CONSANGUINEOUS MARRIAGES IN BAGMARA (RAJSHAHI), BANGLADESH
JLES-Vol-9-No-P-21-27-, December 2014
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